Forensic genetics and genomics: Much more than just a human affair

A comprehensive review on the diverse disciplines of nonhuman forensic genetics, just published in PLoS Genetics. Indeed, it is a fantastic collaboration with the lab of Antonio Amorim and Angel Carracedo:



Posted in Publications, Research | Tagged | Leave a comment

Heterogeneous recombination among Hepatitis B virus genotypes

A very interesting paper on heterogeneous recombination in Hepatitis B virus, just published in Infection, Genetics and Evolution


Posted in Publications, Research | Tagged | Leave a comment

Eco-evo classification of tumors

Nice to contribute to this consensus statement in Nature Reviews Cancer about classifying tumors according to their ecological and evolutionary features: 


Posted in Publications, Research | Tagged | Leave a comment

Multiregional tumor trees are not phylogenies

Our comment about misusing multiregional trees in cancer is out:

Alves JA, Prieto T, Posada D. 2017. Multiregional tumor trees are not phylogenies. Trends in Cancer: 0.1016/j.trecan.2017.06.004

Here we show that multiregional tumor trees built from bulk mutational profiles ignore intratumor heterogeneity and can lead to wrong conclusions. At the heart of this is the confusion between population trees vs. gene trees (i.e., multiregional tumor trees vs. clonal trees).

Posted in Publications, Research | Tagged | Leave a comment

Lab wedding greetings

After 15 years and 2 sons, I am finally getting married and my lab made the funniest video ever…

Thanks guys! LOL, D


Posted in Social | Leave a comment

Welcome back to Miguel Arenas, now as RyC fellow!

Miguel Arenas just started a PI position here as a Ramon and Cajal fellow, 7 years after defending his PhD in our lab. During his postdoctoral time Miguel has worked in different methodological aspects of population genetics and molecular evolution in Switzerland, USA, Spain and Portugal.. It is a pleasure to have you back Miguel!

Posted in Lab, People | Leave a comment

Welcome to Jose Luis Soto, a new PhD student!

Jose Luis Soto starts today his PhD on cancer population genetics. He got a FPI fellowship associate to pour project CANCERPOP and will be working on understanding intratumoral heterogeneity in colorecta colon cancer from an evolutionary perspective.

Welcome to the lab Jose Luis!!

Posted in Lab, People, PhD | Leave a comment

Iria’s research on the Spanish news

Posted in News, Research | Tagged | Leave a comment

Juan de la Cierva postdocs are out

Spanish postdoctoral fellowships are out (google “Juan de la Cierva 2016″). If you are interested, want to work in cancer evolution (NGS analysis mainly), and can read some Spanish (sorry) let me know! David

Posted in Research | Leave a comment

MINECO Excelence grant awarded to Iria Fernandez Silva!!

Iria Fernandez Silva was awarded a MINECO (Spanish Ministry of Economy and Competitiveness) grant to study speciation and hybridization of marine fishes. This research involves researchers from four different countries and combines genomics, ecology and behavioral observations to study the colorful pygmy angelfishes.

Some links:


Posted in Grants, Research | Tagged | Leave a comment