We have published a new paper in Nature Communications where we show how statistical phylogenetics can help to understand tumoral dynamics over time and space:
We have been awarded an excellence 3-year structural grant for research groups from the Galician government.
So now our GXB group has been stamped as Competitive Reference Group.
We want to thank Xunta de Galicia for this support
Congratulations to Nuria for passing with honors her Ph.D. viva!
Monica Valecha (India) and Fabián Crespo (Cuba/Ecuador) just arrived to start as PhD students in the CONTRA Marie Curie Innovative Training Network on Computational Oncology. They are going to work on different aspects of cancer evolution.
Welcome to the lab!.
Now we have people from three continents!
Posted in Lab, People
Congratulations to Merly for her PhD awarded today on NGS phylogenomics! You’ve been a GREAT student. Good luck for your postdoc at UC Santa Cruz. We’ll miss you…
New paper just out @GenomeMedicine! We report the impact of sequencing depth (and sampling effort) towards variant detection, genotype accuracy, clonal inference and phylogenetic reconstruction from single-cell cancer data.
NGSphy, our tool for simulating NGS reads along gene trees or genome-wide along a species tree with multiple gene families, is now published in Bioinformatics.
Source code, full documentation, and tutorials including a “Getting started” guide are available at http://github.com/merlyescalona/ngsphy
Both stability-constrained and structure-constrained substitution models are required to realistically predict the effect of mutations during protein evolution. A great study with Ugo Bastolla’s lab just published in Molecular Biology and Evolution,